June 19th, Robert E.
Urol Clin North Am. The data presented herein, although highly supportive for a protective role of various nutrients against bladder cancer, are far from definitive.
Prospective randomized trials with a large sample size, longer follow-up, and an extended duration of treatment are needed to clarify the association between micronutrients and cancer protection. With these caveats in mind, several recommendations can be made.
Simple measures, such as drinking more fluids especially watercan have a profound impact on the incidence of bladder cancer. Vitamins are being extensively studied in chemopreventive trials for different cancers.
There is strong evidence for a chemoprotective effect of vitamin A in bladder cancer. Because liver toxicity is a possibility with long-term administration, the dose should be decreased to 16, IU after 3 years.
Vitamin B6 has been studied in several clinical trials in bladder cancer. The US-based Veterans Administration cooperative study found benefit for vitamin B6 when given as a single agent.
Data for vitamins C and E are insufficient to recommend either agent as stand-alone treatment. Nonetheless, each of these vitamins is known to have beneficial effects, including improved function of the immune system.
It is possible that only a small percentage of patients with bladder cancer respond to vitamins B6, C, or E, yet each is safe, nontoxic, and inexpensive.
In an effort to pool the efficacy of individual agents and to increase the power of study, the authors evaluated the combination of vitamins A, B6, C, and E in a double-blind trial. A large-volume study along similar lines is being conducted.
Among the numerous other compounds and dietary substances purported to have chemopreventive effect, soybeans, garlic, and green tea stand out as having the greatest promise and can freely be recommended to patients. For synthetically synthesized agents such as celecoxib, piroxicam, or DFMO, recommendations must be deferred until the results of clinical trials are conclusively in favor of their use.
Many of the dietary factors found to be protective against bladder cancer are being investigated in other cancers and are beneficial to general health. Although naturally occurring nutrients are ideal, especially because the delicate balance of various micronutrients might be impossible to synthesize in the laboratory, the general population finds it easier to take vitamin supplements.
Unfortunately, dietary changes such as decreasing fat and increasing fruit and vegetable intake are more difficult to initiate. There is a mistaken notion that simply because an agent is naturally occurring, it cannot be as beneficial as taking a substance synthesized in the laboratory.
Even in a high-risk group such as nuclear-bomb survivors in Japan, high consumption of vegetables and fruit is protective against bladder cancer . Encouraging patients to follow an essentially healthy food habit lifestyle will be a significant contribution in the fight against cancer.
Fruit and vegetable intakes are associated with lower risk of bladder cancer among women in the Multiethnic Cohort Study. Fruits and vegetables have been examined for their possible effects on the risk of bladder cancer, as they contain numerous nutrients, phytochemicals, and antioxidants with potentially anticarcinogenic properties.
In a prospective analysis ofolder adults participating in the Multiethnic Cohort Study, the authors examined whether the consumption of fruits and vegetables, or of nutrients concentrated in fruits and vegetables, was associated with bladder cancer risk.
A total of invasive bladder cancer cases men and women were diagnosed over a mean follow-up period of Abe, Hideko. O-nee-Kotoba (‘Queen’s Speech’): Unwanted Speech Practice among Gay Men. The Annual Conference of Asian Studies, Boston, March. Abe, Hideko.
The Study of O-nee-Kotoba (‘Queen’s Speech’) among Gay Men in Japan: Linguistic Analysis of a Play, Chigau Taiko (‘Different Drums’).
The 4th International Gender and Language Conference, Universitat de Valencia. Genealogy & Local History in Buffalo, NY Buffalo Full Text: Listed here are full-text nonfiction books (monographs) and periodicals with a Buffalo, NY connection.
The InfoSnap form for the school year is now available. If you child is returning to the Bordentown Regional School district for the please complete the form to verify your information and sign off on all required school agreements. 1. The Revolutionary War. On July 27, , the Continental Congress created a medical service for a 20,man army and named Dr.
Benjamin Church of Boston as director general and chief physician.
Cancer Research UK Health Behaviour Research Centre, Department of Epidemiology and Public Health, University College London, Gower Street, London, WC1E 6BT, UK. 🔥Citing and more! Add citations directly into your paper, Check for unintentional plagiarism and check for writing mistakes.